Publications

Citations according to google scholar:  http://bit.ly/10TponI

– *** Mandy B. Esch, Gretchen J. Mahler, Michael L. Shuler, Body-on-a-Chip simulation with gastrointestinal and liver tissue suggests that ingested nanoparticles have the potential to cause liver injury. Lab on a Chip, 2014, 14, 3081-3092.

–   *** Mandy B. Esch, Alec Smith, Jean-Mathew Prot, Charlotta Oleaga Sancho, James Hickman, Michael L. Shuler, How Multi-Organ Microdevices Can Help Foster Drug Development. Advanced Drug Delivery Reviews, 2014, 69/70, 158-169. (invited paper

– Chris Frendl, Scott Tucker, Nadeem Kahn, Mandy B. Esch, Shrinidi Kanduru, Thong M. Cao, Andr. S. J. Garc, Michael R. King Jonathan T. Butcher, Endothelial retention and phenotype on carbonized cardiovascular implant surfaces. (2014) Biomaterials, 35, 7714-7723.

– Alec S.T, Smith, Christopher J. Long, Bonnie J. Berry, Christopher McAleer, Maria Stancescu, Peter Molnar, Paula G. Miller, Mandy B. Esch, Jean-Matthieu Prot, James J. Hickman, and Michael L. Shuler, Microphysiological systems and low-cost microfluidic platform with analytics. Stem Cell Research & Therapy, 2013, 4(1), S9, doi:10.1186/scrt370

–   J.H. Sung, M.B. Esch, W.T. McLamb, C. Bernabini, B. Srinivasan, M.L. Shuler and J.J. Hickman, Using PBPK guided “Body-on-a-Chip” Systems to Predict Mammalian Response to Drug and Chemical ExposureExperimental Biology and Medicine (2014), 239, 1225-1239.

–       Cetinkaya, C., Suni I.I., Andreescu, S., Esch, M.B., Cui, W., Jones, D.L., Jones, S., Chojecki, G.S., Stephens, J.D., Vahdat A.S.,  “Conceptual Framework for the Development of a Course in Nano-Micro-Scale Systems Engineering”, Journal of Nano Education, 2013, 5, 1-9

–      Sung, J.H., Esch, M.B., Prot, J.-M., Long, C.J., Smith, A. Hickman, J., Shuler, M.L. ”Microfabricated Mammalian Organ Systems and Their Integration into Models of Whole Animals and Humans”, Lab on a Chip, 2013, 13 (7), 1201 – 1212.

–    *   Esch, M.B., Sung, J.H., Yang, J. Yu, J., March, J.C., Shuler, M.L. “On Chip Porous Polymer Membranes for Integration of Gastrointestinal Tract Epithelium with Microfluidic ‘Body-on-a-Chip’ Devices”. Biomedical Microdevices, 2012, 14 (5), 895-906.

–     ***  Mahler, G.J., Esch M.B., Tako E., Archer S.D., Glahn R.P., Shuler, M.L. “Oral Exposure to Nanoparticles Affects Essential Nutrient Absorption,”. Nature Nanotechnology, 2012, 7, 264–271.

–       Long, C., Finch, C., Esch, M.B., Anderson, W., Shuler, M.L., Hickman, J. “Design Optimization of Liquid-Phase Flow Patterns for Microfabricated Lung On A Chip”, Annals of Biomedical Engineering, 2012, 40/6, 1255-1267.

–     ** Esch, M.B., Post, D., Shuler, M.L., Stokol, T. “Characterization of Small Diameter In Vitro Endothelial Linings of the Microvasculature,” Tissue Engineering A, 2011, 17, 2965-2971.

–    ***   Esch, M.B., King, T. L., Shuler, M.L. “The Role of Body-On-A-Chip Devices in Drug and Toxicity Studies”, Annual Reviews of Biomedical Engineering, 2011, 13, 55-72.

–       Stokol, T., Esch, M.B., Nishimura, N., Schaffer, C., Daddona, J.L., Post, D.J., Desai, D.P. “Little Channels, Big Disease: Using Microfluidics to Investigate Cancer Metastasis” ASME Conference ProceedingsASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels (ICNMM2011) June 19–22, 2011, Edmonton, Alberta, Canada.

–       Shuler, M.L., Esch, M.B., “Body-on-a Chip: Using Microfluidic Systems to Predict Human Responses to Drugs”, Pure and Applied Chemistry, 2010, 82/8, 1635-1645.

–       Sung, J.H., Esch, M.B., Shuler, M.L. “Integration of in Silico and in Vitro Platforms for the PK-PD Modeling Approach”, Expert Opinion On Drug Metabolism & Toxicology, 2010, 6/9, 1063-1081.

–       Esch, M.B., Sung, J.H., Shuler, M.L. “Challenges, Promises and Future Directions of mCCAs”, Journal of Biotechnology, 2010, 148, 64–69.

–       Mahler, G.J., Esch M.B., Shuler, M.L. “Characterization of a Gastrointestinal Tract Microscale Cell Culture Analog Used to Predict Drug Toxicity ”, Biotechnology & Bioengineering, 2009, 104(1), 193-205.

–       Guillemette M.D., Cui B., Roy E., Gauvin R.J., Esch M.B., Giasson C.J., Carrier P., Deschambeault A., Dumoulin M., Tonar, M., Germain L., Veres T., Auger F.A., “Surface topography induces 3D self-orientation of cells and extracellular matrix resulting in improved tissue function”, Integr. Biol., 2009, 1, 196-204.

–       Esch, M.B.; Kapur, S.; Irizarry, G.; Genova, V. “Influence of Master Fabrication Techniques on the Characteristics of Embossed Microfluidic Channels”, Lab on a Chip, 2003, 121-127.

–     ***  Esch, M.B.; Locascio, L.; Tarlov, M.J.; Durst, R.A. “Detection of Viable Cryptosporidium parvum in a Microfluidic Chip”, Analytical Chemistry, 2001, 73 (13), 2952-2958.

–      ***  Esch, M.B.; Bäumner, A.; Durst, R.A. “Rapid Visual Detection of Viable Cryptosporidium parvum on Test Strips using Oligonucleotide-tagged Liposomes”, Analytical Chemistry, 2001, 73(13), 3162-3167.

–     *  Esch, M.B.; Sukhorukov, V.L.; Kürschner, M.; Zimmermann, U. “Dielectric Properties of Alginate Beads and Bound Water Relaxation Studied by Electrorotation” Biopolymers, 1999, 50, 227-237.

BOOK CHAPTERS

–  Michael L. Shuler, Serina G. Harris, Xinran Li, Mandy B. Esch, Animal Surrogate Systems in Tissue Engineering and Artificial Organs. The Biomedical Engineering Handbook, Ed. Joseph D. Bronzino, CRC Press, Boca Raton, FL, 2012, pp.8/1

– Alec S.T. Smith, Christopher J. Long, Christopher McAleer, Xiufang Guo, Mandy B. Esch, Jean-Mathew Prot, Michael L. Shuler and James J. Hickman, Body-on-a-Chip Technology and Supporting Microfluidics. Human-Based Systems for Translational Research. Editor, R. Coleman. Royal Society of Chemistry. 2013, in print

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